Odoxil (Cefadroxil)

What is Odoxil?

Odoxil is a brand name for cefadroxil, an antibiotic belonging to the cephalosporin class. It is used to treat various bacterial infections by stopping the growth of bacteria. Cefadroxil is a broad-spectrum antibiotic effective against a wide range of gram-positive and gram-negative bacteria.

Uses of Odoxil

Odoxil (cefadroxil) is commonly used to treat:

• Respiratory tract infections such as bronchitis, pharyngitis, and tonsillitis.
• Skin and soft tissue infections (e.g., cellulitis, impetigo).
• Urinary tract infections (UTIs) like cystitis and pyelonephritis.
• Bone and joint infections (e.g., osteomyelitis).
• Bacterial infections in the ears, nose, or throat (ENT infections).

Benefits of Odoxil

• Broad-spectrum antibiotic: Effective against many different types of bacteria.
• Well-tolerated: Usually causes fewer side effects compared to some other antibiotics.
• Versatile use: Effective in treating infections in different parts of the body, including the respiratory tract, skin, and urinary system.

How Does Cefadroxil Work?

Odoxil (cefadroxil) works by inhibiting the bacterial cell wall synthesis. It blocks the formation of peptidoglycan, an essential component of the bacterial cell wall, causing the wall to break down. This leads to the death of the bacteria and the resolution of the infection.

How to Take Cefadroxil?

• Take orally with or without food.
• Drink a full glass of water with each dose.
• Take the medication at evenly spaced intervals to maintain a consistent level of the drug in your body.

Dosage of Odoxil

• The dosage depends on the type and severity of the infection, as well as the patient’s age and weight.
• For adults: Typically, 500 mg to 1 g taken once or twice daily.
• For children: The dosage is usually based on body weight, generally 25 to 50 mg/kg per day, divided into two doses.

Missed Dose and Overdose

• Missed Dose: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose to make up for the missed one.
• Overdose: In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, and diarrhea.

Available Strengths of Odoxil

Odoxil (cefadroxil) is available in the following strengths:

• 250 mg capsules
• 500 mg capsules
• 1 g tablets
• Oral suspension for children, with varying concentrations.

Side Effects 

Common side effects include:

• Nausea
• Diarrhea
• Vomiting
• Stomach upset
• Rash or itching (indicating an allergic reaction)

Serious side effects (less common) may include:

• Severe allergic reactions (e.g., difficulty breathing, swelling of the face, lips, or throat)
• Severe diarrhea (possibly indicating a condition called Clostridium difficile-associated diarrhea)
• Unusual bleeding or bruising
• Dark urine or yellowing of the skin or eyes (possible signs of liver issues)

Interactions of Odoxil

• Probenecid: Can increase the concentration of cefadroxil in the blood.
• Anticoagulants (blood thinners): May increase the risk of bleeding.
• Live bacterial vaccines (e.g., typhoid vaccine): Odoxil may make vaccines less effective.
• Other antibiotics: Combining antibiotics may reduce the effectiveness of one or both drugs.

Precautions of Odoxil

• Allergies: Do not take Odoxil if you are allergic to cefadroxil, other cephalosporins, or penicillins.
• Kidney issues: Dosage may need to be adjusted in patients with renal impairment.
• Pregnancy and breastfeeding: Use only if clearly needed and prescribed by a doctor, as cefadroxil can pass into breast milk.
• Prolonged use: Can lead to fungal or bacterial overgrowth (e.g., oral thrush or yeast infections).

Storage Information

• Store Odoxil at room temperature (below 30°C), away from moisture and direct sunlight.
• Keep out of reach of children.
• If using the oral suspension, refrigerate and discard after 14 days.

Availability in the US and UK

Cefadroxil (the active ingredient in Odoxil) is available under generic names and brand names in both the US and UK. However, the specific brand “Odoxil” may not be widely available in these regions. Cefadroxil, as a generic medication, is commonly prescribed and available in pharmacies.

Frequently Asked Questions

1. Can I take Odoxil with food?

Yes, Odoxil can be taken with or without food. Taking it with food may reduce stomach upset.

2. How long does it take for Odoxil to work?

You may start to feel better within a few days, but it is important to complete the full course of antibiotics as prescribed by your doctor.

3. Can I drink alcohol while taking Cefadroxil?

While there is no direct interaction between alcohol and cefadroxil, it’s advisable to avoid alcohol, as it can increase the risk of stomach upset or dehydration.

4. Is Odoxil safe for children?